ウォルター・ギルバート
Walter Gilbert(1932-)
ようこそ!フリーイラストポートレートと
歴史の停車場いらすとすてーしょんへ
こちらのページではギルバート20世紀に
活躍した世界の化学者XXをお楽しみください
ギルバート
イラストポートレート Syusuke Galleryより
![1932-現在を生きる化学者であり生化学者、物理学者。1977年、マクサム・ギルバート配列決定という新しいDNA配列決定法を開発し、この業績により1980年にはSanger(1918-2013)、Paul Berg(1926-2023)とともにノーベル化学賞を受賞した。バイオテクノロジー企業であるバイオジェン社の共同創設者としてもその名を刻んでいる。](https://illuststation196.com/wp-content/uploads/2024/07/Walter-Gilbert.jpeg)
1977年、マクサム・ギルバート法という
新しいDNA配列決定法を開発
この業績により1980年に
Sanger(1918-2013)、Paul Berg(1926-2023)とともに
ノーベル化学賞を受賞
バイオテクノロジー企業であるバイオジェン社の
共同創設者としてもその名を刻んでいる
![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
いらすとすてーしょんでは化学の部屋より20世紀に活躍した世界の化学者と題してイラストポートレートをお届けします
(参考)18世紀に活躍した世界の化学者たち
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(参考)19世紀に活躍した世界の化学者たち
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19世紀に活躍した世界の化学者(1)はこちら↓
19世紀に活躍した世界の化学者(2)はこちら↓
19世紀に活躍した世界の化学者(3)はこちら↓
(参考)20世紀に活躍した世界の化学者たち
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20世紀に活躍した世界の化学者(1)はこちら↓
20世紀に活躍した世界の化学者(2)はこちら↓
20世紀に活躍した世界の化学者(3)はこちら↓
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さて今回はギルバートをお届けします
DNA配列決定法を開発
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ギルバートはどんな化学者だったの?
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ギルバートは、新しいDNA配列決定法を開発した化学者であり生化学、物理学者でした
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新しいDNA配列決定法を開発??
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ではギルバートの開発したDNA配列決定法を簡単にご紹介します
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マクサム・ギルバート法↓
ギルバートに指導を仰いでいた当時の学生Allan Maxam(1942-)と共に、DNAの塩基配列を化学的に決定する画期的な方法を開発し「マクサム・ギルバート法」と名付けました
その画期的な方法とは、DNA分子を特定の塩基ごとに化学的に切断し、その断片を電気泳動で分離するというものであり、放射性同位体を用いて標識したDNA断片をゲル上で解析することで、塩基配列を読み取ることを可能にしました
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この新しい方法はどう画期的だったの??
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マクサム・ギルバート法は、1,000の塩基配列を数か月で決定できるスピーだったそうです
1980年ノーベル化学賞受賞
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この功績からSanger(1918-2013)、Paul Berg(1926-2023)とともに、ギルバートはノーベル化学賞を受賞します
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![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
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![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
ノーベル賞を受賞するぐらいだから、1,000の塩基配列を数か月で決定できるスピードは、すごいスピードだったってことだよね
![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
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![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
当時では、まさに夢のようなスピードでした
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
ちなみに、ヒトの塩基数ってどれぐらい??
![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
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約30億塩基対あると言われています
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
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![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
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![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
3,000,000,000!?
このマクサム・ギルバート法だと、数ヶ月で1,000塩基だから…ヒトの塩基配列がすべて決定できるのは気が遠くなりそうだ…
![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
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確かにマクサム・ギルバート法では、気が遠くなりますよね
![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
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![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
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![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
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![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
当時はヒトゲノム全体を決定するためには10年以上かかるとされていました
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
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![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
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![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
マクサム・ギルバート法が開発されてから40年以上も経っているから、すでに解明されているか…
![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
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確かに、時間経過からすればその通りですが、マクサム・ギルバート法以降に技術は進化して、現在では次世代シーケンシング技術が開発されていますよ
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
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![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
それはどれぐらいのスピードなの??
![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
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![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
ヒトの塩基数を約30億とすると、現在では約1日で決定するが可能になっています
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
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![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
![](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan.jpeg)
10年…つまり3650日以上かかるとされていたのが、たった1日…
![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
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![](https://illuststation196.com/wp-content/uploads/2022/11/painter.jpg)
ギルバート氏もマクサム氏もまだご存命ですから、このテクノロジーの進化をどのように感じておられるのでしょうか!
次回はマリス
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さて今回の20世紀に活躍した世界の化学者XXギルバートは如何でしたか?
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いらすとすてーしょんでは化学の歴史を彩ってきた偉人たちを…
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これからもご紹介していきます
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どうぞお楽しみに!
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マリスは、PCR(ポリメラーゼ連鎖反応)法を開発した化学者であり生化学者です
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ぜひマリスのイラストポートレートページにもお越しください
20世紀に活躍した世界の化学者たち
化学・新着偉人(It's New)はこちらから
【化学の部屋|テオレル】20世紀に活躍した世界の化学者XXX
【化学の部屋|アレニウス】20世紀に活躍した世界の化学者XXⅨ
【化学の部屋|ジグモンディ】20世紀に活躍した世界の化学者XXⅧ
【化学の部屋|オストヴァルト】20世紀に活躍した世界の化学者XXⅦ
化学の部屋へようこそ
出身国別、都道府県でお届けしています
化学の部屋 Chemist
化学の部屋Chemistへようこそ。SyusukeGalleryよりイラストポートレートをお届けさせていただきます。
広告コーナー
いらすとすてーしょんはGoogle AdSenseの収益により
運営させていただいております
皆様のご理解をよろしくお願い申し上げます
いらすとすてーしょん検索コーナー
いらすとすてーしょん検索コーナーh
いらすとすてーしょん検索コーナー
新着偉人(It's New)
新たに公開のイラストポートレートをご覧ください
【経営者の部屋|大原孝四郎】明治時代編.7New!!
【経営者の部屋|岩井文助】明治時代編.6
2024年パリ オリンピック、パラリンピック開催を記念して「いらすとすてーしょん」ではオリンピックに関連する偉人たちのイラストポートレートをお届けしました↓
9月1日から経営者の部屋より、明治時代編をお届けします↓
いらすとすてーしょん新キャラクター
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2022年より"いらすとすてーしょん"にお立ち寄りいただきありがとうございます
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さて本年いらすとすてーしょんの新キャラクターが誕生しました
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シューちゃんです
![シューちゃんはいらすとすてーしょんのキャラクターです](https://illuststation196.com/wp-content/uploads/2024/01/Syu-chan-1024x1024.jpeg)
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シュー(Syu)です
よろしくね
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3年目を迎えた2024年も皆様に役立つ世界の偉人たちをシューちゃんと共にフリーイラストポートレートをお届けします
いらすとすてーしょんからのお知らせ
![創業76年を迎える総合広告代理業を営む栄光社のイチオシと「いらすとすてーしょん」のコラボレーションが2022年7月1日ついにオープン!イチオシ美術とそのイラストポートレートで贈る作者をぜひご堪能ください](https://illuststation196.com/wp-content/uploads/2022/06/栄光社いらすとすてーしょんコラボPPT-1024x217.jpg)
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いらすとすてーしょん「Syusuke Gallery」
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「イチオシ」で取り上げられた美術のその作者を
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皆様のお越しをお待ちしております